News/Events

Affinity tag removal is an important consideration for project design

Affinity tag removal is an important consideration for project design

Workflows for tackling challenging protein projects often utilize an affinity tag approach. In previous posts, we have discussed the purpose of utilizing affinity tags in recombinant protein production, the importance of selecting the proper tag for your specific protein target, and the importance of tag placement that can influence protein expression, purification, and functionality. Our final post in this series will discuss removal of affinity tags.

Eukaryotic Signal Sequences

Eukaryotic Signal Sequences

A eukaryotic signal sequence is a series of amino acids that targets a protein to the secretory pathway.

Celebrate Memorial Day with Proteos

Celebrate Memorial Day with Proteos

As Memorial Day approaches, Proteos would like to extend our warmest wishes to you and your loved ones for a safe and enjoyable weekend.

Methods for Determining Aggregation

Methods for Determining Aggregation

SDS-PAGE and analytical HPLC-SEC are valuable methods for detecting protein aggregation.

Considerations for Minimizing Aggregation

Considerations for Minimizing Aggregation

Previously, the importance of protein solubility during the production process was discussed. Here we continue with considerations that can improve protein solubility and reduce aggregation.

Protein Solubility and Aggregation

Protein Solubility and Aggregation

Solubility is an important consideration at any stage of recombinant protein production.

Intact Mass Analysis Now Available

Intact Mass Analysis Now Available

Proteos is excited to announce the expansion of our services to include intact mass analysis using LC ESI-MS.

Happy Holidays from Proteos!

Happy Holidays from Proteos!

Thank you to our valued customers for your business and support in 2022. We wish you a joyous holiday season and look forward to working with you in 2023.

Happy Thanksgiving!

Happy Thanksgiving!

Proteos would like to wish you a very Happy Thanksgiving!

Fusion Proteins for Mammalian Cell Expression

Fusion Protein Removal Following Mammalian Cell Expression

Fusion proteins are often used to increase the expression and solubility of the target protein but may negatively affect the functionality of the target protein in biochemical or structural studies.

Let Proteos Help You Achieve Your 2022 Goals

Let Proteos Help You Achieve Your 2022 Goals

Proteos stands ready to help you complete your 2022 discovery research goals before the end of the year.

Fusion Protein Placement for Mammalian Cell Expression

Fusion Protein Placement for Mammalian Cell Expression

The design and placement of a fusion protein partner relative to the protein of interest must be critically considered and empirically tested since it can significantly affect protein expression and function.

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