CRO Services

With decades of combined experience, our highly skilled scientists are ready to get started on your protein or antibody project.  We work closely with our customers to develop customized, detailed workflows so that you will know each step of your project before the work is even initiated.  A dedicated project manager will monitor the project’s progress and communicate important details to you in real time.  All of our processes have been thoroughly validated in-house to ensure high quality results.

Expression Systems

Protein Expression

Mammalian cell, insect cell, and bacterial expression platforms are available for expression of recombinant proteins.  Complete molecular biology services, from construct design to endotoxin free plasmid DNA isolation, are also available.

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Protein Sciences

Protein Purification

A comprehensive selection of protein purification and analysis services for isolation and characterization of recombinant affinity-tagged or native proteins are available.  In addition, we also offer customizable protein analytics packages.

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Antibody Production

Antibody Production

Expression and purification of full-length IgG antibody, F(ab) and (Fab’)2 antibody fragments, and antibody fusion proteins.  Our antibody production capabilities include construct design, transient mammalian cell expression, utilizing in-house or customer provided expression vectors, and affinity purification. We offer both molecular and enzymatic approaches for generation of F(ab) and (Fab’)2 antibody fragments.

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Assay Services

Assay Services

The baculovirus titer assay is a plate-based flow cytometry assay, that offers a quick reproducible method for determining the number of infectious virus particles/mL.

The thermal shift assay (TSA) is used to measure the thermal denaturation (melting temperature) of proteins under various conditions.  The assay is useful for screening pH, ionic strength, ligand binding, and other formulation additives for their impact on melting temperature. Conditions that increase the melting temperature are considered stabilizing.

We also offer services for running commercially available kit-based colorimetric and fluorometric assays.

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