Announcing NEW enhanced capabilities! We have been acquired by NanoImaging Services (NIS), a leading US-based cryo-EM CRO. Learn about our new services now.

CRO Services

With decades of experience, our highly skilled scientists are ready to work with you to develop a customized, detailed workflow to ensure that you know each step of the project before work is initiated. Dedicated project managers monitor the project and communicate results in real time.

Proteos Services Overview (PDF)

U.S.-Based Contract Research Services

Specializing in recombinant protein expression, purification, recombinant antibody production, and assay services-customized to your project’s exact needs

Recombinant Protein Expression 

Customizable expression services in mammalian, insect, and bacterial systems. Scalable transient production in shake flask culture in a wide range of scales up to 60 L. 

 

Mammalian Cell Expression 

Industry-leading transient expression services using fully licensed HEK and CHO cell lines for fast, reliable protein production. 

 

Insect Cell Expression 

Baculovirus-mediated expression services using fully licensed Sf9 (Spodoptera frugiperda) and Tni (Trichoplusia ni) insect cell lines to deliver high-yield, scalable protein production for diverse research applications. 

 

Bacterial (E. coli) Expression

E. coli-based expression services deliver fast, affordable production of high-quality recombinant proteins.

 

Protein Purification 

Flexible and scalable protein purification solutions—customized for soluble proteins, protein complexes, and membrane protein targets at low milligram to low gram scale. 

 

Protein Analytics 

Comprehensive protein analytics to characterize, quantify, and evaluate protein samples across multiple dimensions. Analytics packages are fully customizable to best suit your applications. 

 

Recombinant Antibody Production 

The antibody production platform is designed for flexibility, scalability, and precision. Whether working with full length IgG, engineered antibody formats, or antibody fusion proteins, tailored workflows are available to specific project requirements.  

 

Assay Services 

Assay services include baculovirus titer assay, thermal shift assay (TSA), intact mass analysis, commercially available colorimetric and fluorometric assays. These services can be used for stand-alone analysis or integrated into a customized gene-to-protein workflow to meet your specific needs.  

 

Baculovirus Titer Assay 

A plate-based flow cytometry assay for rapid, reproducible titer determination (infectious particles per mL) of baculovirus stocks, enabling infection of insect cells using a calculated MOI (multiplicity of infection).  

 

Thermal Shift Assay 

Thermal shift assay (TSA), also known as Differential Scanning Fluorimetry (DSF), is widely used in structural biology and drug discovery to study the thermal stability and binding properties of proteins, aiding in the characterization and optimization of protein-based research. 

 

Intact Mass Analysis 

Mass spectrometry is a powerful tool for protein characterization. Our intact mass analysis service offers high-accuracy molecular weight determination for confirming the integrity of protein sequences and the identification of post-translational modifications or chemical adducts.  

Frequently Asked Questions

How do I know my information and data will not be shared?

We safeguard personal data privacy and confidential information with non-disclosure requirements and state-of-the-art IT security. In addition, we practice responsible sourcing, giving preference to business partners and suppliers that share our values and ethics standards. 

Do you offer GMP production services?

Proteos does not operate GMP laboratory services. Recombinant proteins produced by Proteos are research grade and are to be used for research purposes only. 

How do I get in touch with someone to discuss a potential project?

Getting in touch with Proteos is easy. Just click on the request a quote button on any webpage, complete the short form, and click submit. One of our expert scientists will quickly review your information and contact you directly for further discussions. 

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