Submissions for this form are closed.

We value your feedback.  Complete the form below and receive a gift card for a free cup of coffee on us.

Cao Z, Wu Y, Liu G, Jiang Y, Wang X, Wang Z, Zhang J, Feng T. α-Synuclein in salivary extracellular vesicles as a potential biomarker of Parkinson's disease.  Neurosci Lett.

2018 Dec 21;696:114-120. doi: 10.1016/j.neulet.2018.12.030. [Epub ahead of print] PubMed PMID: 30579996.

Zhao Y, Keshiya S, Atashrazm F, Gao J, Ittner LM, Alessi DR, Halliday GM, Fu Y, Dzamko N. Nigrostriatal pathology with reduced astrocytes in LRRK2 S910/S935 phosphorylation deficient knockin mice. Neurobiol Dis.

2018 Dec;120:76-87. doi: 10.1016/j.nbd.2018.09.003. Epub 2018 Sep 5. PubMed PMID: 30194047; PubMed Central PMCID: PMC6197399.

Zhang C, Xu Y, Chowdhary A, Fox D 3rd, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM. Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice. Neuropsychopharmacology.

2018 Oct;43(11):2299-2309. doi: 10.1038/s41386-018-0178-6. Epub 2018 Aug 14. PubMed PMID: 30131563; PubMed Central PMCID: PMC6135860.

Liu G, Tian C, Gao L, Cao Z, Feng T. Alpha-synuclein in erythrocyte membrane of patients with multiple system atrophy: A pilot study. Parkinsonism Relat Disord.

2018 Sep 11. pii: S1353-8020(18)30397-3. doi: 10.1016/j.parkreldis.2018.09.012. [Epub ahead of print] PubMed PMID: 30228038.

Milanese C, Cerri S, Ulusoy A, Gornati SV, Plat A, Gabriels S, Blandini F, Di Monte DA, Hoeijmakers JH, Mastroberardino PG. Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson's disease. Cell Death Dis.

2018 Jul 26;9(8):818. doi: 10.1038/s41419-018-0848-7. PubMed PMID: 30050065; PubMed Central PMCID: PMC6062587.

Hinkovska-Galcheva V, Kelly R, Manthei KA, Bouley R, Yuan W, Schwendeman A, Tesmer JJG, Shayman JA. Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A(2). J Lipid Res.

2018 Jul;59(7):1205-1218. doi: 10.1194/jlr.M084012. Epub 2018 May 3. PubMed PMID: 29724779; PubMed Central PMCID: PMC6027918.

Abe A, Hiraoka M, Shayman JA, Ohguro H. A fluorometric assay for lysosomal phospholipase A2 activity using fluorescence-labeled truncated oxidized phospholipid. Anal Biochem.

2018 May 15;549:164-170. doi: 10.1016/j.ab.2018.03.024. Epub 2018 Mar 30. PubMed PMID: 29605449.

Teplyakov A, Obmolova G, Luo J, Gilliland GL. Crystal structure of B-cell co-receptor CD19 in complex with antibody B43 reveals an unexpected fold. Proteins.

2018 May;86(5):495-500. doi: 10.1002/prot.25485. Epub 2018 Mar 10. PubMed PMID: 29490423.

Oba-Yabana I, Mori T, Takahashi C, Hirose T, Ohsaki Y, Kinugasa S, Muroya Y, Sato E, Nguyen G, Piedagnel R, Ronco PM, Totsune K, Ito S. Acidic organelles mediate TGF-β1-induced cellular fibrosis via (pro)renin receptor and vacuolar ATPase trafficking in human peritoneal mesothelial cells. Sci Rep.

2018 Feb 8;8(1):2648. doi: 10.1038/s41598-018-20940-x. PubMed PMID: 29422602; PubMed Central PMCID: PMC5805675.

Polinski NK, Volpicelli-Daley LA, Sortwell CE, Luk KC, Cremades N, Gottler LM, Froula J, Duffy MF, Lee VMY, Martinez TN, Dave KD. Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson's Disease in Rodents. J Parkinsons Dis.

2018;8(2):303-322. doi: 10.3233/JPD-171248. PubMed PMID: 29400668; PubMed Central PMCID: PMC6004926.

Warmoth, M. The Effect of Targeted Vaccination Against Mycobacterium Avium ssp. Paratuberculosis (MAP) in a Multiple Sclerosis Mouse Model: Implications for Causation. bioRxiv

2017 October 12. bioRxiv 202275; doi: This article is a preprint and has not been peer-reviewed.

Mollenhauer B, Batrla R, El-Agnaf O, Galasko DR, Lashuel HA, Merchant KM, Shaw LM, Selkoe DJ, Umek R, Vanderstichele H, Zetterberg H, Zhang J, Caspell-Garcia C, Coffey C, Hutten SJ, Frasier M, Taylor P; Investigating Synuclein Consortium of the Michael J. Fox Foundation for Parkinson's Research. A user's guide for α-synuclein biomarker studies in biological fluids: Perianalytical considerations. Mov Disord.

2017 Aug;32(8):1117-1130. doi: 10.1002/mds.27090. Epub 2017 Jul 22. Review. PubMed PMID: 28734051; PubMed Central PMCID: PMC5638072.

Stolzenberg E, Berry D, Yang, Lee EY, Kroemer A, Kaufman S, Wong GCL, Oppenheim JJ, Sen S, Fishbein T, Bax A, Harris B, Barbut D, Zasloff MA. A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity. J Innate Immun.

2017;9(5):456-463. doi: 10.1159/000477990. Epub 2017 Jun 27. Erratum in: J Innate Immun. 2018;10(1):82. PubMed PMID: 28651250; PubMed Central PMCID: PMC5865636.

Flavin WP, Bousset L, Green ZC, Chu Y, Skarpathiotis S, Chaney MJ, Kordower JH, Melki R, Campbell EM. Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins. Acta Neuropathol.

2017 Oct;134(4):629-653. doi: 10.1007/s00401-017 1722-x. Epub 2017 May 19. PubMed PMID: 28527044.

Teplyakov A, Obmolova G, Malia TJ, Gilliland GL. Crystal structure of CD27 in complex with a neutralizing noncompeting antibody. Acta Crystallogr F Struct Biol Commun.

2017 May 1;73(Pt 5):294-299. doi: 10.1107/S2053230X17005957. Epub 2017 Apr 26. PubMed PMID: 28471362; PubMed Central PMCID: PMC5417320.

Obmolova G, Teplyakov A, Malia TJ, Wunderler N, Kwok D, Barone L, Sweet R, Ort T, Scully M, Gilliland GL. Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography. Mol Immunol.

2017 Mar;83:92-99. doi:10.1016/j.molimm.2017.01.005. Epub 2017 Jan 21. PubMed PMID: 28119207.

Landeck N, Buck K, Kirik D. Toxic effects of human and rodent variants of alpha-synuclein in vivo. Eur J Neurosci.

2017 Feb;45(4):536-547. doi: 10.1111/ejn.13493. Epub 2017 Jan 11. PubMed PMID: 27893183.

Crimmins DL, Herries EM, Ohlendorf MF, Brada NA, Garbett NC, Zipfel GJ, Schindler SE, Ladenson JH. Double Monoclonal Immunoassay for Quantifying Human Visinin-Like Protein-1 in CSF. Clin Chem.

2017 Feb;63(2):603-604. doi: 10.1373/clinchem.2016.263236. Epub 2016 Dec 16. PubMed PMID: 27986783.

Abe A, Hiraoka M, Ohguro H, Tesmer JJ, Shayman JA. Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2. J Lipid Res.

2017 Feb;58(2):339-349. doi: 10.1194/jlr.M070730. Epub 2016 Dec 19. PubMed PMID: 27993948; PubMed Central PMCID: PMC5282950.

Maruyama S, Nakamura K, Papanicolaou KN, Sano S, Shimizu I, Asaumi Y, van den Hoff MJ, Ouchi N, Recchia FA, Walsh K. Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture. EMBO Mol Med.

2016 Aug 1;8(8):949-66. doi: 10.15252/emmm.201506151. Print 2016 Aug. PubMed PMID:27234440; PubMed Central PMCID: PMC4967946.

Curtis RC, Custis JT, Ehrhart NP, Ehrhart EJ, Condon KW, Gookin SE, Donahue SW. Combination Therapy with Zoledronic Acid and Parathyroid Hormone Improves Bone Architecture and Strength following a Clinically-Relevant Dose of Stereotactic Radiation Therapy for the Local Treatment of Canine Osteosarcoma in Athymic Rats. PLoS One.

2016 Jun 22;11(6):e0158005. doi: 10.1371/journal.pone.0158005. eCollection 2016. PubMed PMID: 27332712; PubMed Central PMCID: PMC4917251.

Glukhova A, Hinkovska-Galcheva V, Kelly R, Abe A, Shayman JA, Tesmer JJ. Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun. 2015 Mar 2;6:6250. doi: 10.1038/ncomms7250. PubMed PMID: 25727495; PubMed Central PMCID: PMC4397983.

Grädler U, Czodrowski P, Tsaklakidis C, Klein M, Werkmann D, Lindemann S, Maskos K, Leuthner B. Structure-based optimization of non-peptidic Cathepsin D inhibitors. Bioorg Med Chem Lett.

2014 Sep 1;24(17):4141-50. doi: 10.1016/j.bmcl.2014.07.054. Epub 2014 Jul 25. PubMed PMID: 25086681.

McAvoy T, Lassman ME, Spellman DS, Ke z, Howell BJ, Wong O, Zhu L, Tanen M, Struyk A, Laterza OF.  Quantification of tau in cerebrospinal fluid by immunoaffinity enrichment and tandem mass spectrometry.  Clin Chem. 

2014 Apr;60(4):683-9. doi: 10.1373/clinchem.2013.216515.  Epub 2014 Feb24. PubMed PMID:24566260.

Mondal K, Regnstrom K, Morishige W, Barbour R, Probst G, Xu YZ, Artis DR, Yao N, Beroza P, Bova MP. Thermodynamic and kinetic characterization of hydroxyethylamine β-secretase-1 inhibitors. Biochem Biophys Res Commun.

2013 Nov 15;441(2):291-6. doi: 10.1016/j.bbrc.2013.09.081. Epub 2013 Sep 23. PubMed PMID: 24070613.

Ren Z, Tam D, Xu YZ, Wone D, Yuan S, Sham HL, Cheung H, Regnstrom K, Chen X, Rudolph D, Jobling MF, Artis DR, Bova MP. Development of a novel β-secretase binding assay using the AlphaScreen platform. J Biomol Screen.

2013 Jul;18(6):695-704. doi: 10.1177/1087057113482138. Epub 2013 Mar 29. PubMed PMID: 23543430.

Abe A, Rzepecki PW, Shayman JA. A fluorogenic phospholipid for the detection of lysosomal phospholipase A2 activity.  Anal Biochem. 

2013 Mar 1;434(1):78-83. doi: 10.1016/j.ab2012.11.004. Epub 2012 nov 9. PubMed PMID: 23146589; PubMed Central PMCID: PM3557754.

Gray SK, McGee-Lawrence ME, Sanders JL, Condon KW, Tsai CJ, Donahue SW. Black  bear parathyroid hormone has greater anabolic effects on trabecular bone in dystrophin-deficient mice than in wild type mice. Bone.

2012 Sep;51(3):578-85. doi: 10.1016/j.bone.2012.05.003. Epub 2012 May 11. PubMed PMID: 22584007; PubMed Central PMCID: PMC3412940.

Gray, Sarah K., "Treatment of osteoporosis in a mouse model of Duchenne muscular dystrophy using black bear parathyroid hormone", Master's Thesis, Michigan Technological University, 2012.

Zhang J, Preda DV, Vasquez KO, Morin J, Delaney J, Bao B, Percival MD, Xu D, McKay D, Klimas M, Bednar B, Sur C, Gao DZ, Madden K, Yared W, Rajopadhye M, Peterson JD. A fluorogenic near-infrared imaging agent for quantifying plasma and local tissue renin activity in vivo and ex vivo. Am J Physiol Renal Physiol.

2012 Aug 15;303(4):F593-603. doi: 10.1152/ajprenal.00361.2011. Epub 2012 Jun 6. PubMed PMID: 22674025; PubMed Central PMCID: PMC3423114.

Fournier PA, Arbour M, Cauchon E, Chen A, Chefson A, Ducharme Y, Falgueyret JP, Gagné S, Grimm E, Han Y, Houle R, Lacombe P, Lévesque JF, MacDonald D, Mackay B, McKay D, Percival MD, Ramtohul Y, St-Jacques R, Toulmond S. Design and synthesis of potent, isoxazole-containing renin inhibitors. Bioorg Med Chem Lett.

2012 Apr 15;22(8):2670-4. doi: 10.1016/j.bmcl.2012.03.014. Epub 2012 Mar 11. PubMed PMID: 22450130.

Duong YT, Qiu M, De AK, Jackson K, Dobbs T, Kim AA, Nkengasong JN, Parekh BS.   Detection of recent HIV-1 infection using a new limiting-antigen avidity assay: potential for HIV-1 incidence estimates and avidity maturation studies. PLoS One.

2012;7(3):e33328. doi: 10.1371/journal.pone.0033328. Epub 2012 Mar 27. PubMed PMID: 22479384; PubMed Central PMCID: PMC3314002.

Lacombe P, Arbour M, Aspiotis R, Cauchon E, Chen A, Dubé D, Falgueyret JP, Fournier PA, Gallant M, Grimm E, Han Y, Juteau H, Liu S, Mellon C, Ramtohul Y, Simard D, St-Jacques R, Tsui GC. 3,4-Diarylpiperidines as potent renin inhibitors. Bioorg Med Chem Lett.

2012 Mar 1;22(5):1953-7. doi: 10.1016/j.bmcl.2012.01.044. Epub 2012 Jan 26. PubMed PMID: 22325946.

Gossas T, Vrang L, Henderson I, Sedig S, Sahlberg C, Lindström E, Danielson UH. Aliskiren displays long-lasting interactions with human renin. Naunyn Schmiedebergs Arch Pharmacol.

2012 Feb;385(2):219-24. doi: 10.1007/s00210-011-0718-7. Epub 2011 Dec 23. PubMed PMID: 22193701.

Chen A, Aspiotis R, Campeau LC, Cauchon E, Chefson A, Ducharme Y, Falgueyret JP, Gagné S, Han Y, Houle R, Laliberté S, Larouche G, Lévesque JF, McKay D, Percival D. Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of spirocyclic piperidines. Bioorg Med Chem Lett.

2011 Dec 15;21(24):7399-404. doi: 10.1016/j.bmcl.2011.10.013. Epub 2011 Oct 19. PubMed PMID: 22071301.

Krop M, van Gool JM, Day D, Hollenberg NK, Jan Danser AH. Evaluation of a direct prorenin assay making use of a monoclonal antibody directed against residues 32-39 of the prosegment. J Hypertens.

2011 Nov;29(11):2138-46. doi: 10.1097/HJH.0b013e32834b1978. PubMed PMID: 21881521.

Malia TJ, Obmolova G, Luo J, Teplyakov A, Sweet R, Gilliland GL. Crystallization of a challenging antigen-antibody complex: TLR3 ECD with three noncompeting Fabs. Acta Crystallogr Sect F Struct Biol Cryst Commun.

2011 Oct 1;67(Pt 10):1290-5. doi: 10.1107/S1744309111030983. Epub 2011 Sep 30. PubMed PMID: 22102050; PubMed Central PMCID: PMC3212385.

Clavreul N, Sansilvestri-Morel P, Magard D, Verbeuren TJ, Rupin A. (Pro)renin promotes fibrosis gene expression in HEK cells through a Nox4-dependent mechanism. Am J Physiol Renal Physiol.

2011 Jun;300(6):F1310-8. doi: 10.1152/ajprenal.00119.2010. Epub 2011 Mar 16. PubMed PMID: 21411480.

Abe A, Kelly R, Shayman JA. The measurement of lysosomal phospholipase A2 activity in plasma. J Lipid Res.

2010 Aug;51(8):2464-70. doi: 10.1194/jlr.D007146. Epub 2010 Apr 21. PubMed PMID: 20410020; PubMed Central PMCID: PMC2903829.

Melnyk RA, Tam J, Boie Y, Kennedy BP, Percival MD. Renin and prorenin activate pathways implicated in organ damage in human mesangial cells independent of angiotensin II production. Am J Nephrol.

2009;30(3):232-43. doi: 10.1159/000220260. Epub 2009 May 19. PubMed PMID: 19451703.

Cousin C, Bracquart D, Contrepas A, Corvol P, Muller L, Nguyen G. Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension.

2009 Jun;53(6):1077-82. doi: 10.1161/HYPERTENSIONAHA.108.127258. Epub 2009 Apr 20. PubMed PMID: 19380613.

Abe A, Shayman JA. The role of negatively charged lipids in lysosomal phospholipase A2 function. J Lipid Res.

2009 Oct;50(10):2027-35. doi: 10.1194/jlr.M900008-JLR200. Epub 2009 Mar 25. PubMed PMID: 19321879; PubMed Central PMCID: PMC2739751.

Slon-Usakiewicz JJ, Redden P. Application of frontal affinity chromatography with mass spectrometry (FAC-MS) for stereospecific ligand-macromolecule interaction, detection and screening. Methods Mol Biol.

2009;572:219-30. doi: 10.1007/978-1-60761-244-5_14. PubMed PMID: 20694695.

Cauchon E, Liu S, Percival MD, Rowland SE, Xu D, Binkert C, Strickner P, Falgueyret JP. Development of a homogeneous immunoassay for the detection of angiotensin I in plasma using AlphaLISA acceptor beads technology. Anal Biochem.

2009 May 1;388(1):134-9. doi: 10.1016/j.ab.2009.02.031. Epub 2009 Mar 1. PubMed PMID: 19258005.

Customize This