Whitepaper: Cryo-EM Structure of CYP3A4
Successful cryo-EM structure determination depends on high-quality protein samples. This whitepaper describes a gene-to-structure case study for CYP3A4, a 57 kDa cytochrome P450 monooxygenase.
CYP3A4 is the most extensively studied P450 enzyme due to its role in drug metabolism. This structure data may have a significant impact on drug development and toxicology studies.
Recombinant CYP3A4 was produced by Proteos with structure determination completed at NanoImaging Services (NIS).
Partner with Proteos to find the best expression strategy for your protein.
